The medically unexplained chronic fatigues, including idiopathic chronic fatigue (ICF) and chronic fatigue syndrome (CFS) are debilitating illnesses due to severe impairment of the quality of life, due to their unknown aetiology and the lack of effective therapeutics... Panax ginseng C.A. Meyer is one of the best known medicinal plants worldwide, and has traditionally been used in Asian countries to maintain homeostasis of the body and to enhance vital energy ... These results support our findings that the antioxidant properties of P. ginseng may be responsible for its antifatigue effects.
Ginseng effectively regulates the immune response and the hormonal changes due to stress, thus maintaining homeostasis. In addition to suppressing the occurrence of psychological diseases such as anxiety and depression, ginseng also prevents stress-associated physiological diseases ... Ginseng provides a potential approach to regaining homeostasis after abnormal physiological changes caused by the stress of everyday life. The efficacy of this preparation has been demonstrated in various experiments conducted using human cells and animal models.
The molecular mechanisms of the neuroprotective effects of ginseng in Alzheimer’s disease (AD) including β-amyloid (Aβ) formation, tau hyperphosphorylation and oxidative stress, major depression, stroke, Parkinson’s disease and multiple sclerosis are presented. It is hoped that this discussion will stimulate more studies on the use of ginseng in neurological disorders.
The immune response is the most important defense system protecting the human body from external attacks by microorganisms and toxic chemical compounds ... According to the results of many in vitro studies, ginsenosides exert anti-inflammatory activities in a variety of in vivo animal models of inflammatory diseases, and show promising protective effects in animal models of colitis, alcohol-induced hepatitis, IR injury, and impaired memory diseases.
Panax Ginseng have been used as functional foods or for traditional Chinese medicine for diabetes, inflammation, stress, aging, hepatic injury, and cancer ... Ginseng extract and its saponins exhibit hepatoprotective effects against various hepatic injuries caused by chemical substances and hepatitis viruses.