The Evidence-Based Health Benefits of Ginseng

     Ginseng is known to provide energy, help manage blood sugar and body weight, reduce stress, enhance working memory, support immunity, improve skin conditions, and boost physical, mental, and sexual performance.

Burmeister Ginseng | The many health benefits of American Ginseng

¬† ¬† ¬† Most of the time when you read about ‚ÄúGinseng‚ÄĚ, it often refers to both American (Panax quinquefolius) and Asian or Korean ginseng (Panax ginseng), which belong to the genus Panax and have a somewhat similar chemical makeup. Both Asian and American ginseng contain ginsenosides, which are the substances thought to give ginseng its medicinal properties. But they contain different types in different amounts.¬†

Ginseng contains two significant compounds: ginsenosides and gintonin. These compounds complement one another to provide health benefits.

     Siberian ginseng, or Eleuthero (Eleutherococcus senticosus), is an entirely different plant with different effects. It is distantly related to ginseng, but it does not contain the same active ingredients.

 

Evidence-Based Health Benefits of Ginseng

  • Ginsenosides are the Major Constituents of Ginseng
    They have the unique biological activity and medicinal value, such as anti-tumor, anti-inflammatory, anti-oxidation, and inhibition of cell apoptosis.

  • May Benefit Brain Function
    American Ginseng has been shown to benefit mental functions, prevents neuronal damage and enhances cognitive performance ‚ÄĒ predominantly short-term memory.

  • Could Improve Sexual Performance
    It may improve sexual performance by decreasing oxidative stress in tissues and enhancing blood flow to genital muscles.

  • May Boost the Immune System
    American Ginseng may strengthen the immune system and even enhance the effects of certain vaccinations.

  • May Have Potential Benefits Against Malignant Cells
    Ginsenosides in American ginseng can inhibit apoptosis of malignant cells, helps to eliminate toxic effects of chemotherapeutics to healthy cells, and decreases sickness-related fatigue.

  • May Fight Tiredness and Increase Energy Levels
    It may help fight fatigue and enhance physical activity by lowering oxidative damage and increasing energy production in cells.

  • May Help with Weight Management
    American Ginseng may help with weight management by lowering the absorption of dietary fat. Moreover, it may improve tissues' sensitivity towards insulin.

  • May Improve Heart Health
    It depresses cardiac contractile function (helped to reduce the force at which the heart had to work, while at the same time maintaining the same blood pressure), decreases heart rate and diminishes hypertrophy.

  • May Improve Digestive Health
    American Ginseng attenuates oesophagus damage resulted from acid reflux and prevents the gastric mucosa from potential ulcer formation.

  • May Have Anti-Aging Properties
    It might have an effect on both the chronological and biological aspects of aging due to the antioxidant properties in Ginsenosides. Studies have shown ginseng may improve facial wrinkling by increase Type I pro-collagen synthesis, protect against UV radiation-induced skin damage, and up-regulate hyaluronic acid generation in human skin cells.

  • ¬†May Have Anti-Aging Properties
    American Ginseng might have an effect on both the chronological and biological aspects of aging due to the antioxidant properties in Ginsenosides. Studies have shown ginseng may improve facial wrinkling by increase Type I pro-collagen synthesis, protect against UV radiation-induced skin damage, and up-regulate hyaluronic acid generation in human skin cells.

  • May Have Antimicrobial Properties
    Studies have showed the leaves, roots, and hairy root cultures found in American Ginseng are all sources of antimicrobial compounds.

Burmeister Ginseng | The many health benefits of American Ginseng

How to Take Ginseng

     Ginseng root can be consumed in many ways. It can be eaten raw or you can lightly steam it to soften it. Most often ginseng can be purchased in various dried form, whole root, sliced or coarse ground. To which you can seep a small amount in hot water to make a tea, or added to various recipes like soups and stir-frys. Ginseng can also be consumed as a powder, capsule or extract. How much you should take depends on the condition you want to improve.

Usage

How often should one take American ginseng?

¬† ¬† ¬†American ginseng are most often taken about¬†1‚Äď2 grams of ginseng root (in the forms of powder, tea or capsules) or 200‚Äď400mg of extract are suggested.¬†It‚Äôs best to start with lower¬†amount and increase over time.

     American ginseng is cooler in nature and less stimulating, thus, making it ideal for today’s busy, fast-paced, stressful lifestyles. It is better suited for younger, middle-aged individuals, and can be used daily and long term.

How long does it take to feel the effects of Ginseng? 

     Ginseng doesn't need to build up in your body for you to feel its effect. It could take as little as under an hours or up to 48 hours to notice a difference in how you're feeling.

     Multiple research studies support the benefit of American ginseng at improving sickness-related fatigue. With a dosage of 2,000 mg daily, participants reported notable difference at 4 weeks, but a statistically significant improvement in fatigue at 8 weeks.

Should one take ginseng in the morning or at night?

     Since both American and Asian ginseng can be stimulating (American ginseng is less stimulating by comparison), which can boost physical and mental energy, it may cause sleep issues for some individuals. Thus, it would be preferable to take ginseng earlier during the day.

 

Interactions

     While ginseng appears to be safe in general, people taking certain medications should pay attention to possible drug interactions. If you're pregnant, breastfeeding, or have other medical conditions, please consult your health care provider for more information.

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Supporting Articles

American ginseng. (n.d.). Mount Sinai. Retrieved March 7, 2022, from https://medlineplus.gov/druginfo/natural/967.html

American Ginseng. (n.d.-b). Medline Plus. Retrieved March 7, 2022, from https://medlineplus.gov/druginfo/natural/967.html

Barton DL, Liu H, Dakhil SR, Linquist B, Sloan JA, Nichols CR, McGinn TW, Stella PJ, Seeger GR, Sood A, Loprinzi CL. Wisconsin Ginseng (Panax quinquefolius) to improve cancer-related fatigue: a randomized, double-blind trial, N07C2. J Natl Cancer Inst. 2013 Aug 21;105(16):1230-8. doi: 10.1093/jnci/djt181. Epub 2013 Jul 13. PMID: 23853057; PMCID: PMC3888141.

Jin Y, Kotakadi VS, Ying L, Hofseth AB, Cui X, Wood PA, Windust A, Matesic LE, Pena EA, Chiuzan C, Singh NP, Nagarkatti M, Nagarkatti PS, Wargovich MJ, Hofseth LJ. American ginseng suppresses inflammation and DNA damage associated with mouse colitis. Carcinogenesis. 2008 Dec;29(12):2351-9. doi: 10.1093/carcin/bgn211. Epub 2008 Sep 18. PMID: 18802031; PMCID: PMC2639244.

Lee S, Rhee DK. Effects of ginseng on stress-related depression, anxiety, and the hypothalamic-pituitary-adrenal axis. J Ginseng Res. 2017 Oct;41(4):589-594. doi: 10.1016/j.jgr.2017.01.010. Epub 2017 Jan 24. PMID: 29021708; PMCID: PMC5628357.

Nordqvist, J. (2021, May 16). What are the health benefits of ginseng? Medical News Today. https://www.medicalnewstoday.com/articles/262982

Ong WY, Farooqui T, Koh HL, Farooqui AA, Ling EA. Protective effects of ginseng on neurological disorders. Front Aging Neurosci. 2015 Jul 16;7:129. doi: 10.3389/fnagi.2015.00129. PMID: 26236231; PMCID: PMC4503934.

Sinai, M. (n.d.). American ginseng. Mount Sinai. Retrieved June 20, 2022, from https://www.mountsinai.org/health-library/herb/american-ginseng

Szczuka D, Nowak A, ZakŇāos-Szyda M, Kochan E, SzymaŇĄska G, Motyl I, Blasiak J. American Ginseng (Panax quinquefolium¬†L.) as a Source of Bioactive Phytochemicals with Pro-Health Properties. Nutrients. 2019 May 9;11(5):1041. doi: 10.3390/nu11051041. PMID: 31075951; PMCID: PMC6567205.

Thomas GB, Asher GN, Mounsey A. PURLs: Finally, a way to relieve cancer-related fatigue. J Fam Pract. 2014 May;63(5):270-2. PMID: 24795907; PMCID: PMC4043102.

White DJ, Camfield DA, Ossoukhova A, Savage K, Le Cozannet R, Fança-Berthon P, Scholey A. Effects of Panax quinquefolius (American ginseng) on the steady state visually evoked potential during cognitive performance. Hum Psychopharmacol. 2020 Nov;35(6):1-6. doi: 10.1002/hup.2756. Epub 2020 Sep 8. PMID: 32896022; PMCID: PMC7685123.

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