Clinical Studies — Ginsenosides
Protective effects of ginseng on neurological disorders
Posted by Michael Burmeister on
The molecular mechanisms of the neuroprotective effects of ginseng in Alzheimer’s disease (AD) including β-amyloid (Aβ) formation, tau hyperphosphorylation and oxidative stress, major depression, stroke, Parkinson’s disease and multiple sclerosis are presented. It is hoped that this discussion will stimulate more studies on the use of ginseng in neurological disorders.
- Tags: brain, Ginsenosides, neuroprotection, Panax ginseng
Role of ginsenosides, the main active components of Panax ginseng, in inflammatory responses and diseases
Posted by Michael Burmeister on
The immune response is the most important defense system protecting the human body from external attacks by microorganisms and toxic chemical compounds ... According to the results of many in vitro studies, ginsenosides exert anti-inflammatory activities in a variety of in vivo animal models of inflammatory diseases, and show promising protective effects in animal models of colitis, alcohol-induced hepatitis, IR injury, and impaired memory diseases.
Ginseng, the natural effectual antiviral: Protective effects of Korean Red Ginseng against viral infection
Posted by Michael Burmeister on
The swift emergence of new infectious viruses and drug-resistant variants has limited the availability of effective antiviral agents and vaccines. Thus, the development of broad-spectrum antivirals and immunomodulating agents that stimulate host immunity and improve host resilience is essential. Although ginseng itself can exert direct antiviral effects by inhibiting viral attachment, membrane penetration, and replication, the foremost antiviral activities of ginseng are attributed to the enhancement of host immunity.
American ginseng suppresses inflammation and DNA damage associated with mouse colitis
Posted by Michael Burmeister on
Ulcerative colitis (UC) is a dynamic, idiopathic, chronic inflammatory condition associated with a high colon cancer risk. American ginseng has antioxidant properties and targets many of the players in inflammation ... Results are consistent with this hypothesis. The use of American ginseng extract represents a novel therapeutic approach for the prevention and treatment of UC.
Pharmacological Effects of Ginseng on Liver Functions and Diseases: A Minireview
Posted by Michael Burmeister on
Ginseng, an ancient and famous medicinal herb in the Orient, has been used as a valuable tonic and for the treatment of various diseases including hepatic disorders ... In this regard, ginseng extracts and individual ginsenosides have shown a wide array of beneficial role in the regulation of regular liver functions and the treatment of liver disorders of acute/chronic hepatotoxicity, hepatitis, hepatic fibrosis/cirrhosis, hepatocellular carcinoma, and so on in various pathways and mechanisms.
- Tags: Ginsenosides, liver diseases, Panax ginseng